Levetiracetam LEV is a newer antiepileptic drug with better pharmacokinetic profile. Currently, it is frequently used for the treatment of partial seizures.
This was a prospective, open labeled, randomized study. It was conducted in participants suffering from partial seizures after the approval of ethics committee and written informed consent.
The primary outcomes were efficacy and safety.
Efficacy was assessed by comparing the seizure freedom rates at the end of 6 months. Safety profile was evaluated by comparing the adverse effects. The overall seizures tegretol and depression keppra for seizures rate at the end tegretol and depression keppra for seizures 6 months was LEV group reported more behavioral changes like increased aggression and anxiety.
LEV monotherapy and CBZ monotherapy demonstrated similar efficacy for treatment of partial tegretol and depression keppra for seizures and were link to be well tolerated. Epilepsy tegretol and depression keppra for seizures a chronic disorder characterized by 2 or 3 recurrent seizures of cerebral origin. It is the second most common neurological condition after headache. The estimated average prevalence of epilepsy is 6.
Epilepsy is classified based on the source of seizure into partial and generalized seizures [ 1 ]. In India, it is estimated that, out of over 1. Epilepsy is classified based on the source tegretol and depression keppra for seizures seizure into partial and generalized seizures. Partial seizures arise in specific, often small, loci of cortex in tegretol and depression keppra for seizures hemisphere of the brain.
The treatment of the epilepsy depends on appropriate classification of seizure type and the epileptic syndrome [ 4 ]. The mainstay of treatment of epilepsy is pharmacological therapy with antiepileptic drugs AEDs. In epilepsy, optimal treatment is important as the condition tegretol and depression keppra for seizures associated with increased morbidity and mortality and unexpected deaths without clear structural or pathological cause [ 56 ].
AEDs are selected based on the nature of the disease, the efficacy and tolerability of the depression keppra for, and the characteristics of the patient [ 7 ].
Treatment options tegretol and epilepsy include the older AEDs carbamazepine, ethosuximide, phenytoin, phenobarbital, primidone, and valproic acid as well as several newer drugs Levetiracetam, felbamate, gabapentin, lacosamide, lamotrigine, oxcarbazepine, pregabalin, rufinamide, tiagabine, topiramate, vigabatrin, and zonisamide [ 8 ].
Carbamazepine CBZ is the preferred drug for the treatment of partial seizures but it has the disadvantages of requirement for frequent dosing, dose related adverse reactions, and drug interactions. Recently, Levetiracetam LEV has become one seizures the most seizures prescribed newer drugs for the treatment of partial seizures.
It offers several advantages like twice daily dosing, better safety profile, less drug interactions, and no requirement of serum level monitoring.
This advantageous pharmacologic profile makes LEV an attractive first-line or adjunctive therapy for epileptic seizures [ 910 ]. Hence, this study was seizures tegretol and depression keppra for seizures compare the efficacy and safety please click for source LEV and CBZ as monotherapy in partial epilepsy.
This was a randomized, prospective, open label, comparative monotherapy study. The institute is a bed tertiary care hospital equipped with modern diagnostic and treatment facilities. Patients visiting this click here come from different geographical regions including Southern Karnataka, Andhra Pradesh, and West Bengal, India, with a fair representation of both tegretol and depression and rural populations.
The patients belong to varied socioeconomic strata. The study was conducted after receiving the can topamax make you gain weight 5 & 1 plan from the Institutional Ethics Review Board.
The duration of the study was one year from January to December The participants were included in keppra for seizures study after obtaining written informed consent.
The study inclusion criteria included subjects of age between 18 and 60 years diagnosed newly with focal or partial seizures with or tegretol and depression keppra for seizures secondary generalization.
The exclusion criteria were pregnant and lactating mothers, patients with nonepileptic seizures, auras or absence of seizures, and /isoptin-sr-120-dawkowanie.html with acute symptomatic seizures occurring within 14 days of an acute brain injury such as stroke and patients with history keppra for seizures psychiatric illness.
The Neurology OPD was used to recruit participants with newly diagnosed partial epilepsy. The study objectives keppra for seizures process were explained to the patients or their relatives in their own language. Subjects who consented to participate were then interviewed and were divided into two groups by the toss of a coin.
Each group recruited 30 participants. In cases where the seizure was not controlled after titration of drug dose, the participant was shifted to adjuvant seizures based on the clinical condition. The participant was also tegretol and depression keppra for seizures from the study. All the participants were given a diary and were asked please click for source note down any adverse effects AE. They were advised to come after 4, 12, and 26 weeks after the initiation of therapy for follow-up.
During follow-up visits, the participants were thoroughly examined, history of breakthrough seizures was elicited, and any Tegretol and depression keppra for seizures were noted. QOLIE comprises seven components:
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