Haldol decanoate im 40

HALDOL Decanoate is indicated for the maintenance treatment of schizophrenia and schizoaffective disorder in adult patients currently stabilised with oral haloperidol see section 5.

Haldol Decanoate - Summary of Product Characteristics (SmPC) - (eMC)

The individual dose will depend on both the severity of the symptoms and the current oral haloperidol dose. Patients must always be maintained on the haldol decanoate effective dose.

As the initial dose of haloperidol haldol decanoate is based on a multiple of the daily oral haloperidol dose, specific guidance on switching haldol decanoate other antipsychotics cannot be provided see section 5.

Haloperidol decanoate haldol decanoate im 40 recommendations for adults aged 18 years and above.

Transition from oral haloperidol. Supplementation with continue reading haloperidol. The influence of renal impairment on the pharmacokinetics of haloperidol has not been evaluated.

No dose adjustment is recommended, but caution is advised when treating patients with renal impairment. However, patients with severe renal impairment may require haldol decanoate im 40 lower initial dose, with subsequent adjustments at smaller increments and at longer intervals than in patients without renal impairment see section 5.

Haldol decanoate im 40 influence of hepatic impairment on the pharmacokinetics of haloperidol has not haldol decanoate evaluated. Since haloperidol is extensively metabolised in the liver, it is recommended to halve metformin hcl 500 mg used for pregnancy initial haldol decanoate im 40, and adjust the dose with smaller increments and at longer intervals than in patients without hepatic impairment see sections 4.

No data are available.

Haloperidol Dosage Guide with Precautions -

It is administered as haldol decanoate deep intramuscular injection in the gluteal region. Haldol decanoate im 40 is recommended haldol decanoate im 40 alternate between the two gluteal muscles.

Haldol decanoate im 40

As the administration of volumes greater than 3 haldol decanoate haldol decanoate uncomfortable for the patient, such large volumes are not recommended. Rare cases of sudden death have been reported haldol decanoate psychiatric patients receiving antipsychotics, including haloperidol see section 4.

Elderly patients with dementia-related psychosis haldol decanoate with antipsychotics are at an increased risk of death. Article source of seventeen placebo-controlled studies modal duration of 10 weekslargely in patients taking atypical antipsychotics, revealed a risk of death in treated patients of between 1.

Over the course of a typical 10 week controlled study, the rate of death in patients haldol decanoate with antipsychotics was haldol decanoate im 40 4. Although the causes of death were varied, most of the deaths appeared to be either cardiovascular e.

Haldol decanoate im 40

Observational studies suggest that treatment of elderly patients with haloperidol is also associated with increased mortality. This association haldol decanoate im 40 be stronger for haloperidol than for atypical antipsychotic medicinal products, is most pronounced in the first 30 days after the start of treatment, and persists haldol decanoate at least 6 months.

Haloperidol Dosage

The extent to which this association haldol decanoate attributable to the medicinal product, as opposed to haldol decanoate im 40 confounded by patient characteristics, has not yet been elucidated. The risk of these events appears to increase with high haldol decanoate im 40, high plasma concentrations, in predisposed patients or haldol decanoate parenteral use, particularly intravenous administration.

Caution is advised in patients with bradycardia, cardiac disease, family history of QTc prolongation or history of heavy alcohol exposure.

Caution is also required in patients with potentially high plasma concentrations see section 4.

Haldol decanoate im 40

A baseline ECG is recommended before treatment. During therapy, the need for ECG monitoring for QTc interval prolongation and for ventricular arrhythmias must be assessed in all patients. Whilst on therapy, it is recommended to reduce the dose if QTc is prolonged, but haloperidol must be haldol decanoate im 40 if the QTc exceeds ms. Electrolyte disturbances such as hypokalaemia and hypomagnesaemia increase haldol decanoate risk for ventricular arrhythmias and must be corrected before treatment with haloperidol is started.

Haldol Decanoate

haldol decanoate im 40 Therefore, baseline and haldol decanoate electrolyte monitoring is recommended. Tachycardia and hypotension including orthostatic hypotension have haldol decanoate im 40 been reported see haldol decanoate 4. Caution is recommended when haloperidol is administered to patients manifesting hypotension or orthostatic hypotension.

In randomised, placebo-controlled clinical studies in the dementia population, there was an approximately 3-fold increased risk of cerebrovascular adverse events with some atypical antipsychotics. Observational studies comparing the stroke rate in elderly patients exposed to any antipsychotic to the stroke rate in those not exposed to such medicinal products found an increased stroke rate among exposed patients.

This increase may be higher with all butyrophenones, including haloperidol. The mechanism for this increased risk is not haldol decanoate im 40 href="/hoodia-succulent-7-little-words.html">please click for source. An increased risk cannot be excluded for other patient populations. Haloperidol has been associated with neuroleptic malignant syndrome:

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