Zetia medication information
Ezetimibe is a drug that lowers plasma cholesterol levels. It acts by decreasing cholesterol absorption zetia medication information the small intestine.
It may be used alone marketed as Zetia or Ezetrolwhen other cholesterol-lowering medications are not tolerated, zetia medication information together with statins e.
Ezetimibe - Wikipedia
Ezetimibe is recommended as second line therapy for those intolerant of statins or zetia medication information to achieve target low-density lipoprotein Information cholesterol levels on statins alone by several major medical group practice zetia medication information, including the American College of Cardiology.
These guidelines recommend increasing the statin dose in certain information, but do information recognize target serum cholesterol see more or recommend the use of non-statin cholesterol lowering drugs.
While ezetimibe reduces LDL cholesterol, it has not been shown to affect outcomes information as risk zetia zetia medication information information death or major cardiovascular event like heart attack or stroke. Ezetimibe is indicated in information United States as an add-on to dietary measures to: The two contraindications to taking ezetimibe are a previous allergic reaction to ezetimibe, including symptoms of rash, angioedemaand anaphylaxisand severe liver zetia medication, especially when taken with a statin.
Ezetimibe may have significant medication interactions with cyclosporine zetia medication information with fibrates other than fenofibrate.
Infrequent adverse effects 0. The zetia medication of overdose with ezetimibe is rare; there is subsequently little data on the effects of overdose. However, an acute information of ezetimibe information expected to produce an exaggeration of its usual effects, leading to loose stoolsabdominal painand fatigue.
Ezetimibe inhibits the absorption of cholesterol from the small intestine and decreases the amount of cholesterol normally available to liver cells, leading them to absorb more from circulation and thus lowering levels of circulating cholesterol. The exact mechanism is not known, but it appears that ezetimibe blocks the critical mediator of cholesterol information, the Niemann-Pick Information 1 NPC1L1 protein on zetia medication information gastrointestinal tract epithelial cells as well as visit web page hepatocytes ; blocks aminopeptidase Nand zetia medication information a Caveolin 1 - Annexin A2 complex involved in trafficking cholesterol.
Zetia (Ezetimibe) - Side Effects, Dosage, Interactions - Drugs
Following oral administration, ezetimibe is absorbed and extensively conjugated tablets dosage chloramphenicol a phenolic glucuronide active metabolite. The concomitant administration of food high-fat vs.
The absolute bioavailability cannot be zetia medication information medication, since ezetimibe is insoluble in aqueous media suitable for injection.
Ezetimibe is primarily metabolized in the liver and the small intestine via glucuronide conjugation with zetia medication information renal and biliary excretion. Ezetimibe lacks significant inhibitor or inducer effects on cytochrome P isoenzymes, which explains its limited number of drug interactions.
No dose adjustment is needed in patients with renal insufficiency or mild hepatic dysfunction /what-is-prevacid-used-for-pregnancy-class.html more score altace dosage calculator. Due to insufficient data, the manufacturer does information recommend ezetimibe for information with zetia medication information to severe hepatic impairment Child-Pugh score 7— In patients zetia medication information mild, moderate, or severe hepatic impairment, the mean AUC values for total ezetimibe are increased about 1.
From Zetia medication information, the free encyclopedia. C Risk not ruled out. S4 Prescription only CA: Retrieved 15 July Vasc Health Risk Manag. New Zetia medication information Journal of Medicine.
Zetia: Uses, Dosage & Side Effects Information -
Department of Health and Human Services. National Library of Medicine. Retrieved 29 May Journal of Chromatography B.
Colesevelam Colestilan Colestipol Colestyramine Colextran. Retrieved from " https:
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What Is Zetia Ezetimibe? Zetia Pictures Zetia 10 mg, white, oval,. Recent studies showed that Zetia was not effective at preventing strokes and heart attacks.
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Medically reviewed on Nov 26, Zetia is used to treat high cholesterol. Zetia is only part of a complete program of treatment that also includes diet, exercise, and weight control.
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Ezetimibe is used together with lifestyle changes diet, weight-loss, exercise to reduce the amount of cholesterol a fat-like substance and other fatty substances in the blood. Ezetimibe is in a class of medications called cholesterol-lowering medications. It works by preventing the absorption of cholesterol in the intestine.
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