Centre for Reviews and Dissemination UK ; The authors concluded that tamsulosin improved International Prostate Symptom Score in the short-term compared hytrin vs flomax not working terazosin. High-quality trials were needed to assess the efficacy of tamsulosin in the long term.
Some review limitations made the reliability of the pooled results uncertain, but the overall conclusion was suitably cautious and appears appropriate. To assess hytrin flomax safety and efficacy of tamsulosin not working /cleocin-suspension-40-mg.html terazosin in patients with benign prostate hyperplasia. Not working lists of relevant studies hytrin flomax hytrin vs flomax not working were checked.
Topic experts were contacted. There were no language restrictions. Randomised controlled trials RCTs or quasi-randomised controlled trials that compared tamsulosin with terazosin in men with mild to moderate hytrin vs flomax not working prostate hyperplasia with lower urinary tract symptoms LUTS were eligible for inclusion.
Outcomes flomax not working interest were: Participants who underwent prior prostatectomy, thermotherapy, anti-androgen therapy and catheterisation due to urinary retention were excluded from the review. Also excluded were men with prostate cancer, neurogenic bladder, bladder stone and lower urinary hytrin vs flomax not working infection or cardiac, renal or hepatic insufficiency or dementia. Studies were excluded when participants were taking other medicines such as alpha- or beta-adrenoceptor agonists and antagonists, anticholinergics, antiandrogens and 5-alpha-reductase inhibitors.
Mean age hytrin /how-far-in-advance-should-you-take-dramamine-sailing.html included participants ranged from 61 to 68 years across the studies.
No other participant or study flomax not working were reported. Two reviewers independently selected studies. Any disagreements were resolved by consultation with a third hytrin vs flomax not working. Trials quality was assessed using not working of check this out, allocation concealment, blinding, drop-outs and flomax not working analysis. The authors did not state how many reviewers performed the quality assessment.
Data on the number of outcomes in the intervention and comparator groups were extracted. Meta-analyses hytrin vs flomax not working examined /brahmi-gif-images.html weighted mean difference or risk difference were not working using a fixed-effect model. Heterogeneity was assessed using not working X 2 hytrin flomax.
Inconsistency was evaluated using the I 2 statistic. Where there was significant heterogeneity, a random-effects model was used to pool the data. Subgroup analysis was conducted to assess the effects of hytrin vs flomax not working symptom severity on the outcomes. Sample sizes ranged from 35 to 1, participants.
not working Nine hytrin flomax the included studies were considered to be high quality and three were considered to be low quality. After four weeks of treatment, there was a significant positive effect in favour of tamsulosin compared with not working for International Prostate Symptom Score WMD There was no significant statistical heterogeneity between the trials.
There were no significant differences between groups for the outcomes: Significantly more participants in the terazosin treatment group experienced dizziness RR 0. There was no significant statistical /zofran-8-mg-serve-para-que.html between trials for any of these adverse events. No other adverse events were assessed.
Tamsulosin improved International Prostate Symptom Score in the short-term compared with terazosin. The review addressed a clear question flomax not working was supported by appropriate inclusion criteria. Attempts were made to identify all relevant published trials; unpublished data were not sought and this hytrin have introduced publication bias.
Validity was assessed and considered in the analyses. Flomax not working number of reviewers involved in some but not all aspects of the systematic review process was reported, which potentially introduced reviewer bias.
Some details of the included studies were not working, but information on study participants and trial design such as study duration were limited.
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