Donepezilmarketed under the trade name Ariceptis a medication used in the palliative treatment of Alzheimer's disease. Common side effects include loss of appetite, gastrointestinal upset, diarrhea, difficulty sleeping, vomiting, or muscle cramping. It is donepezil the same as aricept indications developed by Eisai and Pfizer and is sold as a generic by multiple suppliers.
Donepezil acts as is donepezil the same as aricept indications centrally acting reversible acetylcholinesterase inhibitor.
There is no evidence that click here or other similar agents is donepezil the same as aricept indications the course or progression of Alzheimer's disease.
is donepezil the same as aricept indications Food and Drug Administration also approved donepezil for treatment of mild, moderate and severe dementia in Alzheimer's disease. In clinical trials the most common adverse events leading to discontinuation were nauseadiarrheaand vomiting.
Side effects improved with continued use. Donepezil should be used with caution in people with heart diseasecardiac conduction disturbances, chronic obstructive pulmonary diseaseasthmadonepezil cardiac arrhythmias and sick sinus syndrome.
People with peptic ulcer disease or taking NSAIDS should use caution because increased risk of gastrointestinal bleeding was noted. These symptoms may appear more frequent when initiating treatment or increasing the donepezil dose.
Although occurrence of seizures is rare, people who have a predisposition to seizures should be treated with caution. Donepezil aricept indications and reversibly inactivates the /what-is-aldactone-prescribed-for-9-month-old.html, thus inhibiting hydrolysis of acetylcholine.
This increases acetylcholine is donepezil the same as aricept indications at cholinergic synapses. The precise mechanism of action of donepezil in patients with Alzheimer's disease is not fully understood. Just the severity of the loss aricept indications cholinergic neurons of the central nervous system CNS has been found to correlate with the same severity of cognitive impairment.
As of link, Aricept was the world's best-selling Alzheimer's disease treatment. Donepezil has been tested in other cognitive disordersincluding Lewy body dementia[20] and vascular dementia[21] but it is not currently approved for these indications. Donepezil has also been found to improve sleep apnea in Alzheimer's patients. Donepezil has also been studied in patients with mild cognitive impairmentschizophreniaattention deficit disorderpost- Is donepezil the same as aricept indications artery bypass surgery more info impairment, [24] cognitive impairment associated with multiple sclerosisCADASIL syndromeand Down syndrome.
A three-year National Institutes of Health trial in patients with mild cognitive impairment reported donepezil was superior to placebo in delaying rate of progression to dementia during the initial 18 months of the study, but this was not sustained at 36 months. In a secondary analysis, a subgroup of individuals with the apolipoprotein Link genotype is donepezil the same as aricept indications sustained benefits with donepezil throughout the study.
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