Medically reviewed on Nov 15, Excipient information presented when available limited, particularly for generics ; consult specific product source. Ondansetron is a selective 5-HT 3 -receptor antagonist which blocks serotonin, both peripherally on vagal nerve terminals and centrally in the chemoreceptor zofran 8 mg serve para que zone.
Infants 1 to 4 months: Clearance is reduced 2- to 3-fold and the volume of distribution is increased.
The half-life is increased to 20 hours in patients with severe hepatic impairment. Que extent and rate of absorption is greater in women than zofran 8 mg serve para que men. There is slower clearance, a smaller volume of distribution, and higher bioavailability in women. Prevention of nausea and vomiting associated with initial and repeat courses of emetogenic cancer chemotherapy including high-dose cisplatin. Prevention of nausea and vomiting associated with initial and repeat courses of moderately emetogenic cancer chemotherapy.
Radiotherapy-associated nausea and vomiting: Prevention of nausea and vomiting click with radiotherapy in patients receiving either total body irradiation, single high-dose fraction to zofran abdomen, or daily fractions to the abdomen. Expert opinion suggests the utility of ondansetron as an alternative agent in zofran 8 mg serve para que with persistent nausea and vomiting refractory to prokinetic therapy [ACG [Camilleri ]][Camilleri ].
Serve are para que published data evaluating the role of antiemetics, including ondansetron, in the treatment of this condition.
Based on the Society for Ambulatory Anesthesia guidelines for que management of postoperative nauseait is reasonable to administer a 5-HT 3 receptor antagonist for the zofran of postoperative nausea and vomiting when paroxetine classification report prophylactic agent was not utilized or as serve para que therapy when an agent from a different class was utilized as prophylaxis and failed. Based serve para the Society of Obstetricians and Gynaecologists of Canada guideline on nausea and vomiting of pregnancy and the American College of Obstetricians and Gynecologists practice bulletin, the use of ondansetron may be considered in the treatment of severe or refractory nausea and vomiting when preferred agents have failed [ACOG ][Arsenault ].
Data from a small, open-label, pilot study ketoconazole cream usage directions zofran experience suggests the utility of ondansetron in the acute treatment of nausea and vomiting associated serve para que vertigo [Furman ][Rice ].
Hypersensitivity to ondansetron or any component of para que formulation; concomitant use with apomorphine. Carcinoid syndrome- associated diarrhea, severe, refractory alternative agent off-label use: Based on zofran data case reports:. Chemotherapy-induced serve and vomiting, prevention: Single-day IV chemotherapy regimens: All oral formulations except for the oral soluble film: Dosing in zofran 8 mg serve para que prescribing information may not reflect que clinical practice: Non-carboplatin-based regimens alternative agent:
2018 ©