Lithium what arealso known as lithium saltsare primarily used as a psychiatric medication. Common side effects include increased urinationshakiness of the hands, and increased thirst.
In the nineteenth century, uses lithium was used in people what are the had gout, epilepsyand cancer. Lithium is used primarily for bipolar disorder. Lithium carbonate treatment was previously considered to be unsuitable for children; however, more recent studies show its effectiveness for treatment of early-onset bipolar disorder in children as young as eight. The required dosage is slightly less than the toxic level, requiring close monitoring drug blood levels of lithium carbonate during treatment.
Lithium is recommended for the treatment of schizophrenic what are the uses of lithium drug only after other antipsychotics have failed and it has limited what are the uses of lithium drug when used alone. If therapy with antidepressant does not fully treat the symptoms of major depressive disorder MDD then a second augmentation agent is sometimes added to the therapy.
Despite not being approved by the FDA for use as an augmentation agent with any antidepressant click the following article the treatment of MDD, lithium has nevertheless been prescribed for this purpose since the 's and is one of the few augmentation agents for antidepressants to demonstrate efficacy in treating MDD in multiple randomized controlled trials.
Those who use lithium should receive regular serum level tests and should monitor thyroid and kidney function for abnormalities, as it interferes what are the uses of lithium drug the regulation of sodium and water levels in the body, and can cause dehydration.
Dehydration, which is compounded by heat, can result in increasing lithium levels. The dehydration is due to lithium inhibition of the action of antidiuretic hormonewhich normally enables the kidney to reabsorb water from urine. This causes lithium inability to concentrate urine, leading to consequent loss of body water and thirst. Lithium concentrations in whole blood, plasma, serum or urine may be measured using instrumental techniques as a guide to therapy, to confirm the what are the uses of lithium drug in potential poisoning victims or to assist in the forensic click at this page in a case of fatal overdosage.
Serum lithium concentrations are usually in the go here. Doses are adjusted to achieve plasma concentrations of 0.
Sources for the following lists. In addition what are the uses of lithium drug tremors, lithium treatment appears to be a risk factor what are development of parkinsonism the uses, although what are the uses of lithium drug causal mechanism remains unknown.
What are the uses of lithium drug side effects of lithium are dose-dependent. The lowest effective dose is used to limit the risk of side effects. The rate of hypothyroidism is around six times higher in people who take lithium.
Low thyroid hormone levels in turn increase the likelihood of developing depression. People taking lithium thus should routinely be assessed for hypothyroidism and treated with synthetic thyroxine if necessary.
Because lithium competes with the what are the uses of lithium drug for the read more hormone lithium drug the kidney, it increases water what are the uses of lithium drug into the urine, a condition called nephrogenic diabetes insipidus.
Clearance of lithium by the kidneys is usually successful with what are the uses of lithium drug diuretic medications, including amiloride and triamterene. Lithium is also believed to permanently affect renal function [ how? Lithium is a teratogenwhat are the uses of lithium drug birth defects in a small number of newborn babies.
Lamotrigine seems to be a possible alternative to lithium in pregnant women for the treatment source acute bipolar depression or for the management of bipolar patients with normal mood. Valproic acid and carbamazepine also tend to be associated with teratogenicity.
While it appears to be safe to what are the uses of lithium drug while breastfeeding a number of guidelines list it as a contraindication [4] including the British National Formulary. Lithium has been associated with several forms of kidney injury. Chronic kidney disease is found in about one-third the uses people undergoing long-term lithium treatment, according to one study.
Lithium plasma concentrations are known to be increased with concurrent use of diuretics —especially loop diuretics such as furosemide drug thiazides —and non-steroidal anti-inflammatory drugs NSAIDs please click for source as ibuprofen.
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