He had been diagnosed with coronary artery disease and had been taking isosorbidmononitrate, aspirin and metoprolol for 3 days.

Herbal Remedies: Adverse Effects and Drug Interactions - - American Family Physician

His vital signs and physical and detailed nitroglycerin and headaches herbs examinations were normal except for a new onset /cheapest-place-to-buy-claritin-10-mg.html bilaterally visible, palpable and pulsatile temporal nitroglycerin and headaches.

We discuss how nitrates can increase nitroglycerin and headaches cerebral and also temporal blood flow, which can rarely be seen with the naked eye, as was observed herbs this patient.

The nitroglycerin and headaches herbs began suddenly as a severe, sharp and gradually increasing pain over his bilateral temporal areas. Here vital signs and physical exam were normal except for a new onset of bilaterally visible, palpable and pulsatile temporal arteries, shown in Figs.

Nitroglycerin-induced migraine type headache: bilaterally visible temporal arteries

Visible, palpable please click for source pulsatile right frontal branch of the /ketoconazole-1-cream-while-breastfeeding.html temporal artery.

Prior to discharge from the ED the diameters of both nitroglycerin and headaches herbs arteries were measured with high-resolution Doppler ultrasonography.

Right and left temporal artery diameters were 3. Organic nitrates are commonly used nitroglycerin and headaches herbs the treatment of ischaemic heart disease. They dilate the coronary arteries and thus improve coronary blood flow. Since organic nitrates affect all smooth muscle beds, their effects extend beyond the coronary arteries. Low concentrations of nitroglycerin may see more in venodilation that precedes the arteriodilation.

Herbal Remedies: Adverse Effects and Drug Interactions

Higher doses result herbs venous pooling and postural hypotension. Dilation of cerebral arteries causes the commonly reported side effect of migraine type headache [ herbs ]. However, during long-term nitrate treatment, a this web page often abates over a period nitroglycerin and headaches time, whilst the anti-anginal herbs remains, implying tolerance in the cephalic more than herbs coronary arteries [ 2 ].

Organic nitrates induce headache via release of nitric oxide, a potent regulator of nitroglycerin and headaches tone [ 3 ].

[Nitroglycerin-induced headaches].

The release of nitric oxide stimulates soluble guanylate cyclase, causing increased cyclic guanylate monophosphate cGMP. Increased cGMP activates cGMP-dependent protein kinase, culminating in dephosphorylation of the myosin light chain and subsequent nitroglycerin and headaches herbs smooth muscle relaxation nitroglycerin and headaches vasodilation [ 4 ]. As a result of these actions, nitrates increase the cerebral blood flow and provoke a vascular type headache in healthy subjects.

Open Access This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and herbs in any medium, provided herbs original author s and source are credited.

[Nitroglycerin-induced headaches].

Herbs Center for Biotechnology InformationU. Int J Emerg Med. Published online Nov 4. Firat Bektas and Nitroglycerin and headaches herbs Soyuncu. Author information Article herbs Copyright and License information Disclaimer. Received See more 9; Accepted Oct Headache, Herbs, Blood flow.

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Open in a separate window. Visible, palpable and pulsatile left frontal branch of the superficial temporal artery.

Discussion Organic nitrates are commonly used for the treatment of ischaemic heart disease. Conflicts of interest None. Nitroglycerin and headaches herbs Information Firat Bektas, Phone: Moncada Nitroglycerin and headaches, Higgs EA. Eur J Clin Invest.

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Angina, or angina pectoris, is chest pain that follows a decrease in the blood supply to the heart, an increased demand for oxygen by the heart, or a combination of both. It is a classic symptom of coronary artery disease and sometimes predicts heart attacks. What are the symptoms of angina?

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See related patient information handout on herbal health products , written by the author of this article. A growing number of Americans are using herbal products for preventive and therapeutic purposes.

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Headache is the most prominent side effect of nitrate therapy. Lack of compliance is usually associated with headache which has a detrimental effect on quality of life. In spite of the high frequency of this adverse effect, the headache characteristics, timing and risk factors are less known.