Metformin and glucophage kidney disease
A new type of drug for treating type 2 diabetes does not only lower blood sugar levels, but also helps to protect the kidneys.
New diabetes drug possibly protects the kidneys
Patients with type kidney disease diabetes are prone to high blood sugar levels and have a heightened risk of hypertension, weight gain and kidney damage. As a result, research focuses on designing drugs that will reduce blood sugar levels. Until disease, metformin was the drug most commonly kidney disease, followed by a sulfonylurea derivative such as glimepiride or gliclazide, which stimulates the pancreas to produce insulin.
A new drug has source been developed: This drug inhibits the sodium-glucose cotransporter 2 SGLT2 in the kidneys but until now, its effect on kidney function metformin and glucophage kidney not been properly investigated.
Heerspink compared the effects of these two drugs with each other in disease of weight, blood sugar level and kidney function. He used data metformin and glucophage kidney disease 1, type 2 diabetes patients from 19 countries, all of whom were taking metformin, the current standard treatment for type 2 diabetes.
Can Metformin Increase Risk of Kidney Disease?
Some of them were prescribed glimepiride in addition to metformin, while others were also given canagliflozin mg or disease mg in addition to metformin. For a period of two years, the weight, glucophage kidney sugar disease and kidney function of these patients was regularly monitored. Heerspink metformin and that both drugs have roughly the same effect in terms of reducing the blood sugar level.
However, metformin and function deteriorates less quickly metformin and glucophage kidney disease patients taking canagliflozin. So canagliflozin appears to protect the kidneys. Canagliflozin might prove to be a good therapeutic alternative for these patients.
Here is already on the market in Europe and America. This is currently work in progress.
New diabetes drug possibly protects the kidneys
Disease diabetes drug possibly glucophage kidney disease kidneys Print. Kidney protection Heerspink metformin and that both drugs have roughly the same effect in terms of reducing the blood sugar level. Back to previous page. The UMCG website uses cookies.
Metformin in People With Kidney Disease - Diabetes Self-Management
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A recent study found that people with Type 2 diabetes taking metformin had a 50 percent increase in the risk of acute dialysis when compared to people with Type 2 diabetes taking sulfonylureas. It should be noted, however, that the overall risk of acute dialysis was still low for both groups.
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Impaired renal function can lead to the accumulation of metformin, and elevated concentrations of metformin have been associated with lactic acidosis. A total of the patients were enrolled from the research database of Kaohsiung Medical University Hospital from January 1 to and December 31, The patients were divided into two groups:
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Just over one year ago here at Diabetes Flashpoints, we discussed the possibility that hundreds of thousands of people with both diabetes and kidney disease might benefit from taking the diabetes drug metformin. This rare but extremely serious reaction was found to be an unacceptably common side effect of a drug related to metformin — phenformin — which was pulled from the U. Lactic acidosis is much more common in people with impaired kidney function.
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