Granisetron is indicated kytril pediatric the prevention of delayed nausea and vomiting associated with chemotherapy and radiotherapy. Granisetron is indicated in children aged 2 years and above dosage the prevention kytril pediatric dosage treatment of acute nausea and vomiting associated with chemotherapy. The dosage should be diluted to 5 ml per mg. Further maintenance doses of Granisetron may be administered at least 10 minutes apart. The maximum dose to be administered read article 24 hours should not kytril pediatric dosage 9 mg.
Kytril pediatric efficacy of parenteral granisetron may be enhanced by an additional intravenous dose of an adrenocortical steroid e. The safety and efficacy of kytril pediatric dosage in children aged 2 years and click at this page has been well established for the prevention and treatment control of acute nausea and vomiting associated with chemotherapy.
One additional dose may be administered within a 24 hour-period if required. This additional dose should not kytril pediatric dosage administered until at least 10 minutes after the initial infusion.
The maximum dose of Granisetron to be administered over 24 hours should not exceed 3 mg. For kytril pediatric prevention of PONV, administration should be completed prior to induction of anaesthesia. Currently available kytril kytril pediatric dosage dosage are described in section 5. kytril pediatric dosage
There is insufficient clinical evidence to recommend administration of dosage solution kytril pediatric dosage injection to children dosage prevention and treatment of post-operative article source and vomiting. There are no dosage precautions required for its use in either elderly patients or those patients kytril pediatric dosage renal or hepatic impairment.
There is no evidence to date for an increased incidence of adverse events in patients with hepatic disorders. On the basis of its kinetics, whilst no dosage adjustment is necessary, granisetron should be used continue reading a certain amount of caution in this patient group see section 5. Administration may be as either a slow intravenous injection over 30 seconds or kytril pediatric dosage an intravenous infusion diluted in kytril pediatric dosage - 50 ml kytril pediatric dosage fluid and administered over 5 minutes.
As granisetron may reduce lower bowel motility, patients with signs of sub-acute intestinal obstruction should be monitored following its kytril pediatric dosage.
In patients with pre-existing arrhythmias or cardiac conduction disorders this might lead link clinical consequences. There have been reports of serotonin syndrome with the use of 5-HT 3 antagonists either alone, but mostly in combination with other serotonergic drugs including selective serotonin reuptake kytril pediatric dosage SSRIsand serotonin kytril pediatric reuptake dosage SNRIs.
Appropriate observation of patients for serotonin syndrome-like symptoms is dosage.
Kytril pediatric dosage studies in healthy subjects, no evidence of any interaction has been indicated between granisetron and benzodiazepines lorazepamneuroleptics haloperidol or anti-ulcer medicinal products cimetidine. Additionally, granisetron has not shown any apparent medicinal product interaction with emetogenic cancer chemotherapies.
There is limited amount of data from the kytril pediatric dosage of granisetron in pregnant women. Animal studies do kytril pediatric dosage indicate direct or indirect harmful effects with respect to reproductive toxicity see section 5. Dosage a precautionary measure, it is preferable to avoid the use of granisetron during pregnancy.
It is unknown whether granisetron or its metabolites are excreted kytril pediatric dosage human milk. As a precautionary measure, breastfeeding should not be advised during treatment with Granisetron.
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