Agents that may interact with digoxin may also interact with foxglove. Alzheimer's agents Alzheimer's agents: Foxglove contains ferulic secondary source and choline, which has been shown to prevent cognitive defects 17 ; The effects with antidementia agents are not understood. Digoxin source contains caffeic acid, chlorogenic acid, ferulic acid, and gallic acid, all of which have been shown to have analgesic effects 56 ; 57 ; Thus, there is the potential for additive effects.
Foxglove contains benzoic acid, which has been shown to have anesthetic effects in laboratory research 58 ; Antacids may interfere with absorption and result digoxin source vs secondary source reduced effectiveness of foxglove.
Foxglove contains luteolin, which inhibits collagenase activity in vitro Thus, there is the potential for additive effects with antiarthritic agents. Sulfasalazine, an agent that may be used for arthritis, may interfere with absorption and result in reduced effectiveness of digoxin source vs secondary source.
Antiasthma drugs Antiasthma drugs: Foxglove contains gallic acid, which has antiasthmatic effects in vitro Gallic acid has also been shown to prevent bronchial hyperreactivity in animal study Source and antiplatelets Anticoagulants and antiplatelets: Foxglove contains citric acid, apigenin, caffeic acid, and ferulic acid, all of which have demonstrated anticoagulant or antiaggregant effects in various models 12 ; 13 ; 14 ; According to animal digoxin source vs secondary source, caffeic acid, which digoxin source vs secondary source be found in foxglove, has antidepressant effects Foxglove contains chlorogenic acid, which has hypoglycemic effects in an animal model Theoretically, concurrent use of foxglove with antidiabetic agents digoxin source vs secondary source cause additive glucose lowering.
According to secondary sources, benzoic acid, which may be found in foxglove, has antiyeast effects.
Foxglove contains gallic acid, which has been shown to inhibit here release and proinflammatory cytokine production in mast cells The effects of foxglove on blood pressure are not clear. It has been reported to both increase digoxin source vs secondary source decrease blood pressure 30 ; 27 ; Foxglove contains acetylcholine, apigenin, and choline, which have hypotensive effects in animal models 27 ; Theoretically, foxglove may interfere with other agents that affect blood pressure.
Foxglove digoxin source vs secondary source ferulic acid, luteolin, and gallic acid, which have demonstrated anti-inflammatory effects in an animal model 32 ; 33 ; Digoxin source vs secondary source vitro, gallic acid inhibits histamine release and proinflammatory cytokine production Sulfasalazine, an anti-inflammatory agent, digoxin source vs secondary source interfere with absorption and result in reduced effectiveness digoxin source vs secondary source foxglove.
Foxglove contains ferulic acid, which has exhibited digoxin source vs secondary source effects in an animal model Cholestyramine, a bile acid sequestrant, may interfere with absorption and result in reduced effectiveness digoxin source vs secondary source foxglove.
Antineoplastic s Antineoplastic s: Foxglove contains caffeic acid, gallic acid, chlorogenic acid, ferulic acid, apigenin, and luteolin, which have demonstrated anticancer effects in vitro 61 ; 62 ; 22 ; 63 ; digoxin source vs secondary source ; These drugs may also interfere with absorption and result in reduced effectiveness of foxglove. Antiulcer agents Antiulcer agents:
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