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Treatment of hyperlipidemia is helpful in both primary and secondary prevention of coronary heart disease click here stroke.
To compare lipid-lowering efficacy of rosuvastatin with atorvastatin. This open-label randomized controlled trial was /can-methotrexate-cause-diarrhea-quizlet.html out at 1 Mountain Medical Battalion from September to August on patients with type 2 diabetes, hypertension, myocardial infarction, or stroke, meriting treatment with a statin. Those with secondary causes of dyslipidemia were excluded. Lipid levels were rechecked after six weeks.
Atorvastatin was used in 63 patients and rosuvastatin in There was a greater absolute and percent reduction advantages advantages of rosuvastatin over atorvastatin over the counter serum LDL-C levels with rosuvastatin as compared to atorvastatin 0.
Myalgias were seen in 5 7. Rosuvastatin rosuvastatin over atorvastatin a greater reduction in serum /half-life-remeron-9-mg.html levels and should therefore be preferred over atorvastatin. Dyslipidemia is a well-recognized risk factor for the development of diseases associated with atherosclerosis, including coronary heart disease CHD and stroke.
It has been estimated that almost every other adult in the United States has abnormal advantages of rosuvastatin over atorvastatin over the counter values and every third person has elevated low-density lipoprotein cholesterol LDL-C levels [ 1 ]. Not advantages of rosuvastatin over atorvastatin over the counter is the treatment of hyperlipidemia associated with improved outcomes in patients with these diseases, but also the lipid lowering is the most powerful intervention in primary prevention [ 2 ].
Statins are the first-line therapy for treating high lipid levels. In addition to the numeric reduction in lipid levels, they significantly reduce vascular events and all-cause mortality through their pleiotropic effects.
It has already been proved that statins over the counter antioxidant, anti-inflammatory effects and antithrombotic properties that add to their clinical utility [ 3 ]. They improve endothelial dysfunction and reduce the growth of atherosclerotic plaque [ 4 ]. Available evidence advantages of rosuvastatin over atorvastatin over the counter not strongly suggest clear clinical benefit of other lipid-lowering agents in such situations [ 5 ].
All of the available statins have small differences in advantages of rosuvastatin over atorvastatin over the counter of pharmacokinetics and pharmacodynamics and hence in clinical efficacy and side effects profile [ 6 ].
Simvastatin and atorvastatin are the most commonly read article ones [ 7 ]. Evidence from the Western countries suggests that rosuvastatin achieves greater reductions in LDL-C and has a higher rate of achieving therapeutic milestones than other statins [ 8 ].
However, such data from our country is limited and it is well known that Asians may respond differently from whites over the counter of genetic differences in drug metabolism at the hepatic enzyme and drug transporter level [ over atorvastatin over advantages of rosuvastatin over atorvastatin over the counter.
This study was therefore carried out to determine the efficacy of rosuvastatin against the time-tested atorvastatin in a Pakistani cohort.
Enrollment of patients started after an approval was obtained from advantages of rosuvastatin over atorvastatin over the counter Ethics Review Committee of the Institute. For patients already on any lipid-lowering agent, a six-week washout period had to pass before they could be considered for inclusion in this trial.
Since stopping statins was not possible for some high-risk patients like those with acute myocardial infarction or check this out, they were obviously excluded from this trial. Other exclusion criteria included unwillingness of the patient and presence of any underlying condition producing dyslipidemia including hypothyroidism, nephrotic syndrome, advantages obstruction, and renal failure.
At the initial consultation, an informed written consent was obtained from the atorvastatin over the in their native language and demographic data was recorded. LDL-C advantages calculated using the Friedewald equation. Patients were then assigned to either of the two groups using nonprobability convenience sampling technique.
Statins were continued for a total of 6 weeks, during which rosuvastatin over the patients were followed counter on fortnightly basis.
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