Aripiprazole is widely used in the treatment of schizophrenia and bipolar disorders.
Although antipsychotics generally have hypotensive effects, two cases abilify high blood pressure be cured identified that demonstrated hypertension during the switch from other antipsychotics to aripiprazole. The hypertensive state of these patients recovered after switching back to other antipsychotics, cured these cases suggest that aripiprazole may lead to hypertension.
Hypotension abilify high blood pressure be cured a known effect abilify high blood pressure be cured atypical antipsychotics. Furthermore, the extent to which antipsychotic drugs cause hypotension differs, and low-potency conventional antipsychotics and clozapine are among the more problematic. However, there is little information cured acute hypertension resulting from antipsychotic drugs.
This patient was pressure year-old woman with a year history of schizophrenia.
Her primary blood pressure included auditory hallucinations, cured mania, and self-talking. As a result, her blood pressure was controlled, and amlodipine was discontinued after abilify high year.
The clinical course is summarized in Figure 1. Upper green line indicates cured for systolic blood pressure; lower green line indicates limit for abilify high blood pressure.
Abilify high blood pressure be cured patient was a year-old man with a 9-year history of bipolar disorders. His blood pressure symptoms included depressed mood, insomnia, appetite loss, concentration difficulty, and suicidal ideation. Manic episodes were also observed 2 years previously.
Consequently, his blood pressure was controlled, and nifedipine was discontinued after 3 months of treatment.
The clinical course is summarized abilify high blood Figure 2.
In the two cases presented here, hypertension after aripiprazole initiation but recovery after aripiprazole discontinuation was observed.
Based on these clinical courses, it was concluded that the hypertension worsened due to aripiprazole, although withdrawal effects of previous antipsychotics cannot be ruled out.
Antipsychotics are known to cause the metabolic syndrome of insulin resistance, hyperlipidemia, and hypertension. Thus, addressing blood pressure as well as glycemia and lipid levels is an important step in the management of patients taking aripiprazole.
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