Sertraline is a selective serotonin reuptake inhibitor SSRI zoloft medication dosage elderly well established antidepressant and anxiolytic activity. Sertraline was significantly more effective than placebo and was as effective as fluoxetine, nortriptyline zoloft medication dosage elderly imipramine in elderly patients.
During one trial, amitriptyline was significantly more effective see more sertraline mean reduction from baseline on one of six primary outcomes [HDRS]although no quantitative data were provided. Subgroup analysis of zoloft medication dosage elderly from zoloft medication dosage article source randomised, double-blind trial in elderly patients with major depressive disorder suggests that vascular zoloft medication dosage elderly, diabetes mellitus or arthritis does not affect the antidepressant effect of sertraline.
Secondary endpoints from these clinical trials suggest that sertraline has significant benefits over nortriptyline in terms of quality of life. In addition, significant zoloft medication dosage elderly favouring sertraline in comparison with nortriptyline and fluoxetine have been recorded for a number of cognitive functioning parameters.
Zoloft medication dosage elderly is generally well tolerated in elderly patients with major depressive disorder and lacks the marked anticholinergic effects that characterise the adverse event profiles of tricyclic antidepressants TCAs.
The tolerability profile of sertraline is generally similar in younger and elderly patients.
Sertraline has a low potential for drug interactions at the level of the cytochrome P enzyme system. In addition, no dosage adjustments are warranted for elderly patients solely based on age.
Since elderly patients are particularly prone to the anticholinergic effects of TCAs as a class, SSRIs such /aricept-5-mg-tablet-ulkongkg.html sertraline are likely zoloft medication zoloft medication elderly be a better choice for the treatment of major depressive disorder in this dosage elderly group.
In zoloft medication dosage elderly, sertraline may have advantages over the SSRIs paroxetine, fluoxetine and fluvoxamine in elderly patients because zoloft medication dosage elderly the drug's comparatively low source for drug interactions, which is of importance zoloft medication dosage elderly patient groups such as the elderly who are likely to receive more than one drug zoloft medication dosage elderly.
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