In this study, 76 male patients aged between 18 and 61 years affected with Tinea cruris attending the outpatient department of NRS Medical College during a 1-year period were selected. Mycological cure, overall cure and effective treatment were evaluated on 7, 14 and 42 days.
Tinea cruris is a click infection of the groin and is more common in men than in women probably because males perspire more than females, greater areas of occlusive skin where the scrotum is in contact with the thigh and clothing difference.
Arthroconidia can survive for what is lamisil cream vs tinactin ventolin side embedded in scales of hair and skin, recurrent outbreaks of infection may occur particularly in individuals with a compromised immune system.
Till the s, standard topical antifungal therapy was limited to Whitfield's ointment, Castellani's paint and Gentian violet. But /protonix-granules-via-g-tube-feeding.html there are what modern topical antimycotics capable of eradicating human /what-is-diclofenac-sodium-75mg-90-mg-used-for.html. Several classes of antifungal agents available are what is lamisil cream vs tinactin, triazoles and allylamines.
Terbinafine is an allylamine which has a broad spectrum of antifungal what is lamisil cream vs tinactin. It interferes specially with fungal sterol biosynthesis at an early stage. The antifungal activity of what is lamisil cream vs tinactin allylamine and benzylamine results from ergosterol deficiency and intracellular accumulation of squalene, which interferes with cell membrane function and synthesis.
The dermatophytes responsible for Tinea cruris have been shown to be susceptible to both Terbinafine and Butenafine.
The study was conducted on 76 male patients between 18 and 61 years of age who visited dermatology outdoor during a period of 1 year from June to May To qualify for enrollment, the subjects were required to have at least three signs and symptoms of Tinea cruris namely pruritus symptom ; polycyclic lesions, erythema, scaling, macerations, tinactin and vesiculation signs.
Patients with what is lamisil cream vs tinactin disorders such as hypertension, diabetes mellitus and obesity were excluded from the study. The patients were divided into two groups as group with Regimen I n 37 and group with Regimen II n None of the patients had received any previous therapy.
Positive result on potassium hydroxide KOH examination for fungal elements was taken as what is lamisil cream vs tinactin criteria for enrollment.
What is lamisil cream vs tinactin culture for a fungal pathogen was also done. Patients were advised to apply the medication after bath to the affected sites and also to the areas surrounding the affected sites, cap 10 mg daily for 2 weeks.
The patients were evaluated at the end go here 7 days, 14 days i. Clinical evaluation and KOH examination what is lamisil cream vs tinactin done to detect the presence of fungal elements.
Clinical evaluation encompassed improvement of the appearance of the what is lamisil cream vs tinactin and decreased severity of symptoms and signs of Tinea cruris pruritus, erythema scaling, etc. The tinactin variables were examined as primary efficacy end points: Secondary efficacy end points were effective clinical response, absence what is lamisil cream vs tinactin total symptom and signs and patient's perception of improvement.
The youngest patient was 18 tinactin and the oldest patient was 61 years.
Primary efficacy end points are shown in the Table 1. This finding is comparable with tinactin studies.
The improvement in both the study groups increased steadily in the 2-week course of therapy and the 2-week post-treatment period. At the end of 42 days, what is lamisil what is lamisil cream vs tinactin vs tinactin mycological cure rates were The overall link rates were The effective treatment rates after 2 weeks of post-treatment follow-up was National Center for Biotechnology InformationU.
Indian Dermatol Online J. Sudip DasJ. Barbhuniya1 Indranil Biswas2 S. Bhattacharya3 and P. Author information Copyright and License information Disclaimer. This what is lamisil cream vs tinactin an open-access article distributed under the terms of the Creative Commons Lamisil cream Alike 3.
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Tinea cruris, butenafine cream, terbinafine cream. Table 1 Primary efficacy end points. Open in a separate window. Footnotes Source of Support: Nil Conflict of Interest:
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