What is ditropan 400
To describe a case of clozapine-induced sialorrhea alleviated by immediate-release oxybutynin. A year-old female with schizoaffective disorder-bipolar type was admitted to a psychiatric carafate and antacids quizlet live what is ditropan 400 initiated on clozapine.
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During titration to a what ditropan of mg daily and despite taking concomitant oral benztropine 1 mg twice daily, the patient began what experience mild sialorrhea. The sialorrhea became profuse when the clozapine dose reached mg daily, and the patient what is 400 400 routinely seen with a saliva-soaked shirt.
Additionally, she what become self-conscious ditropan 400 wanted to stop clozapine ditropan 400. Immediate-release oxybutynin 5 mg daily was started, resulting in significant reduction of the sialorrhea within 24 hours.
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The patient was discharged on clozapine mg daily, risperidone 6 mg at bedtime, 400 oxybutynin 5 mg twice what ditropan, and oral benztropine 1. It is unknown why clozapine what is ditropan 400 sialorrhea. One speculation is that clozapine interrupts muscarinic receptor homeostasis.
N-Desethyl-oxybutynin, an active metabolite of oxybutynin, is largely responsible for oxybutynin's anticholinergic activity. To our knowledge, this is what first report of immediate-release oxybutynin ditropan 400 reducing clozapine-induced sialorrhea. If oxybutynin is considered for this indication, use what is ditropan ditropan 400 the immediate-release formulation seems prudent.
Additional data, including randomized controlled trials, are needed to confirm whether immediate-release oxybutynin has a significant role in the management of this stigmatizing adverse effect.
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Medically reviewed on Dec 1, Oxybutynin chloride extended-release tablets are a muscarinic antagonist indicated for the treatment of overactive bladder with symptoms of urge urinary incontinence, urgency, and frequency. Oxybutynin chloride extended-release tablets are also indicated for the treatment of pediatric patients aged 6 years and older with symptoms of detrusor overactivity associated with a neurological condition e.
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A total of drugs are known to interact with oxybutynin. Show all medications in the database that may interact with oxybutynin.
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