Given the current debate and growing public concerns on selective serotonin reuptake inhibitors SSRIs and birth defects generated cymbalta generic availability continue reading Food and Drug Administration warnings, we sertraline pregnancy to quantify the association between first-trimester exposure to sertraline, a first-line treatment, and the the effects of sertraline on pregnancy of congenital malformations in a cohort of depressed the effects. This was a population-based cohort study in Quebec, Canada, through Major malformations overall and organ-specific malformations in the first year of life were identified.

Analyses were adjusted for potential confounders. Among the 18, eligible pregnancies, were exposed to sertraline, to other SSRIs, and to non-SSRI antidepressants during the first trimester of pregnancy.

Sertraline

Sertraline use was not statistically significantly associated with the risk of overall major malformations when compared to nonuse of antidepressants. Exposure to SSRIs other than sertraline during the first sertraline pregnancy of pregnancy was associated with craniosynostosis RR, 2.