Available forms Available by prescription only Capsules: Initially, 1 mg P. Usual maintenance dose is 6 to 15 mg daily in divided doses. If other antihypertensives or diuretics are added to prazosin prazosin herbal interactions, reduce dose of prazosin to 1 or 2 mg t.
Initially, 2 mg P. Selectively and competitively inhibits alpha-adrenergic receptors, causing arterial and venous dilation, reducing peripheral vascular resistance and blood pressure.
Alpha blockade in nonvascular smooth muscle causes relaxation, notably in prostatic tissue, prazosin herbal interactions reducing urinary symptoms in men with benign prostatic hyperplasia. Variable absorption from GI tract.
Antihypertensive effect begins in about 2 hours. Full antihypertensive effect may not prazosin herbal interactions for 4 prazosin herbal interactions 6 weeks. Metabolized extensively in liver. Plasma half-life is 2 to 4 hours. Antihypertensive effect lasts less than 24 prazosin herbal interactions. Contraindications and precautions No known contraindications.
Use cautiously in patients receiving antihypertensives and in those with chronic renal failure. Monitor blood pressure regularly.
Other highly protein-bound drugs: Prazosin is highly bound to plasma proteins and may prazosin herbal interactions with these drugs. Reduces effects prazosin herbal interactions drug. May decrease WBC count. Overdose and treatment Toxicity may prazosin herbal interactions prazosin herbal interactions and drowsiness.
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