Ondansetron mouth dissolving tablets formulation
Jagdale Sunil Agio Pharmaceuticals Ltd.
Formulation and Characterization of Patient-Friendly Dosage Form of Ondansetron Hydrochloride
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Asian J Pharm ;1: The preparation of orally disintegrating tablets using a hydrophilic waxy binder. Int J Pharm ; Net [Cited August ]. In-vitro and in-vivo evaluation of a fast-disintegrating lyophilized dry emulsion tablet containing Griseofulvin.
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Formulation and Characterization of Patient-Friendly Dosage Form of Ondansetron Hydrochloride
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Journal of Chemical and Pharmaceutical Research (ISSN : 0975-7384)
Tyagi Associate Editor s Dr. Jadon Editorial Members Prof.
Abstract Ondansetron Hcl is a ondansetron mouth dissolving tablets formulation receptor 5-HT3 antagonist used in the prevention of chemotherapy induced nausea and vomiting. The demand for orally disintegrating tablet has ondansetron mouth dissolving tablets formulation growing, especially for geriatric and pediatric patients because of swallowing difficulties.
Taste Masking of Ondansetron Hydrochloride and Formulation of Fast Dissolving Tablets | Abstract
The FTIR studies showed drug ondansetron mouth dissolving tablets formulation tablets formulation carrier were compatible. These were then compressed into tablets by direct compression method with using different superdisintegrants like Shieffield ODT, Crosspovidone, Pharmaburst, Polyplasdone XL, Ludiflash. All formulations ondansetron mouth evaluated for disintegration time, wetting time, weight variation, percentage friability and in vitro dissolution rate.
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Ondansetron hydrochloride is an intensely bitter antiemetic drug used to treat nausea and vomiting following chemotherapy. The purpose of the present work was to mask the taste of ondansetron hydrochloride and to formulate its patient-friendly dosage form.
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Ondansetron Hydrochloride OSH is a sparingly water-soluble drug. In this investigation fast dissolving tablets FDTs of ondansetron were prepared using different superdisintegrants by sublimation method. FDTs were evaluated for physicochemical properties and in vitro dissolution.
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