Medically reviewed on Nov 1, Nitroglycerin is indicated for the acute relief of an attack or acute prophylaxis of angina pectoris due to coronary artery disease. Administer one tablet under the tongue or in the buccal pouch at zero first sign of an acute anginal attack.
Allow tablet to dissolve without swallowing. One additional tablet may be administered every 5 minutes until sublingual is nitroglycerin. No more than three tablets are recommended within a click period.
If the pain persists after a total of 3 tablets in a minute period, or if the pain is different than is typically experienced, seek prompt medical coumadin discharge instructions. Nitroglycerin may be used prophylactically 5 to 10 minutes prior to engaging in activities that might precipitate an acute attack. For patients with xerostomia, a small sip of water prior to placing the tablet under the tongue may help maintain mucosal hydration and aid dissolution of the tablet.
Do not use nitroglycerin in nitroglycerin 0 3 mg sublingual zero who are taking PDE-5 Inhibitors, such as avanafil, sildenafil, tadalafil, vardenafil hydrochloride. Concomitant use can cause severe hypotension, syncope, or myocardial ischemia [see Drug Interactions 7. Do nitroglycerin 0 3 mg sublingual zero use nitroglycerin in nitroglycerin 0 3 mg sublingual zero who are taking the soluble guanylate cyclase stimulators, such as riociguat. Concomitant use can cause hypotension.
Nitroglycerin is contraindicated in patients with severe anemia large doses of nitroglycerin may cause oxidation of hemoglobin to methemoglobin and could exacerbate anemia. Nitroglycerin may precipitate or aggravate increased intracranial pressure and thus should not be used in patients nitroglycerin 0 3 mg nitroglycerin 0 3 mg sublingual zero zero possible increased intracranial pressure e.
Nitroglycerin is nitroglycerin 0 3 mg sublingual zero in patients who are allergic to nitroglycerin, other nitroglycerin 0 3 mg sublingual zero or nitrites or any excipient. Nitroglycerin is contraindicated in patients with acute circulatory failure or shock. Excessive use may lead to the development of tolerance.
Only the smallest dose required for effective relief of the acute angina attack should be used. A decrease nitroglycerin 0 3 mg sublingual zero therapeutic effect of sublingual nitroglycerin may result from use of long-acting nitrates.
Nitroglycerin 0 3 mg sublingual zero hypotension, particularly with upright posture, may occur with small doses of nitroglycerin particularly in patients with constrictive pericarditis, aortic or mitral stenosis, patients who may be volume-depleted, or are already hypotensive.
Hypotension induced by nitroglycerin may be accompanied by paradoxical bradycardia and increased angina pectoris. Nitroglycerin produces dose-related headaches, especially at the start of nitroglycerin therapy, which may be severe and persist but usually subside with continued use. The following adverse reactions are discussed in more detail elsewhere in the label:.
Nitroglycerin 0 3 mg sublingual zero, dizziness, weakness, palpitation, and other manifestations of postural hypotension may develop occasionally, particularly in erect, immobile patients. Marked sensitivity to the please click for source effects of nitrates manifested by nausea, vomiting, weakness, diaphoresis, pallor, and collapse may occur at therapeutic doses.
Syncope due click nitrate vasodilatation nitroglycerin 0 3 mg sublingual zero been click here. Flushing, drug rash, and exfoliative dermatitis have been reported in patients receiving nitroglycerin 0 3 mg sublingual zero therapy. Nitroglycerin is contraindicated in patients who are using a selective inhibitor of cyclic guanosine nitroglycerin 0 3 mg sublingual zero cGMP -specific phosphodiesterase type 5 PDE
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