Minocycline is recognized as an effective, well-tolerated therapy in rheumatoid arthritis RAalthough its use has minocycline for arthritis 30 days associated minocycline for arthritis 30 days the development of cutaneous hyperpigmentation. To assess the clinical determinants and frequency of minocycline-induced hyperpigmentation in patients with RA.
A minocycline for arthritis 30 days medical record review of all patients with RA seen in 2 academic rheumatology practices was performed to identify subjects who had received days least 1 month of minocycline for minocycline therapy. Patient demographics, disease singulair 10mg generic buscopan, medication use, and medication side effects were abstracted from the medical record.
Using Cox proportional hazards regression and restricting the analysis to the initial minocycline course, we examined arthritis association of patient factors and minocycline for arthritis 30 days medications with the development of hyperpigmentation. Minocycline-induced hyperpigmentation led to the read more of treatment in 3 patients, with 12 additional patients receiving a dose reduction.
There were no significant associations of sex, minocycline for minocycline for arthritis 30 days 30 days, concomitant prednisone, or aspirin use with the development of hyperpigmentation. Minocycline-induced hyperpigmentation is a common complication seen with minocycline use in the treatment of RA, and seems to increase with age.
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