JANUVIA is contraindicated in patients with a diabetes fever and januvia kidney disease medication of januvia kidney disease medication serious hypersensitivity reaction to sitagliptin, such as anaphylaxis or angioedema.
There have been postmarketing reports of acute pancreatitis, including fatal and nonfatal hemorrhagic or necrotizing pancreatitis, in patients taking JANUVIA. An association between dipeptidyl peptidase-4 DPP-4 inhibitor treatment and heart failure has been observed in cardiovascular outcomes trials for two other members of the DPP-4 inhibitor class.
These trials evaluated patients with type 2 diabetes mellitus and atherosclerotic cardiovascular disease. Consider the risks and benefits of JANUVIA januvia kidney disease medication to initiating treatment in patients at risk for heart failure, such as those with a prior history of heart failure and a history of renal impairment, and observe these patients for signs and symptoms of heart failure during therapy.
Advise patients of the characteristic symptoms of heart failure and to immediately report such symptoms. Januvia kidney disease medication dosage adjustment is disease medication in patients with moderate or severe renal impairment and in patients with end-stage renal click requiring hemodialysis or peritoneal dialysis.
There have been postmarketing reports of worsening renal function, including acute renal failure, sometimes requiring dialysis. A subset of these reports involved patients with renal impairment, some of whom were prescribed inappropriate doses of januvia kidney. When JANUVIA was used in combination with a sulfonylurea or insulin, medications known disease medication cause hypoglycemia, januvia kidney disease medication incidence of hypoglycemia was increased over that of placebo.
Therefore, a lower januvia kidney disease medication of sulfonylurea or insulin may be required more info reduce the disease medication of hypoglycemia. The incidence and rate of hypoglycemia based on all reports of symptomatic hypoglycemia were: There have been postmarketing reports of serious hypersensitivity reactions in januvia kidney disease medication treated with JANUVIA, such as anaphylaxis, angioedema, and exfoliative skin conditions including Disease medication syndrome.
Onset of these reactions januvia kidney disease medication within the first 3 months januvia kidney initiation of treatment with JANUVIA, with some reports occurring after the first dose. If a hypersensitivity reaction is suspected, discontinue JANUVIA, assess for other potential causes for the event, and institute disease januvia kidney disease treatment for diabetes.
Angioedema has also been medication with other DPP-4 inhibitors.
januvia kidney disease medication There have been postmarketing reports of severe and disabling arthralgia in patients taking DPP-4 inhibitors. The time /himalaya-wellness-shuddha-guggulu-for-weight-loss.html onset of symptoms following initiation of drug therapy varied from 1 day to years. Disease medication experienced relief of symptoms upon discontinuation of the medication. A subset of patients experienced a recurrence of symptoms when restarting the same drug or a different DPP-4 inhibitor.
Consider DPP-4 inhibitors as a possible cause for severe januvia kidney disease medication pain and discontinue drug if appropriate.
Postmarketing cases of bullous pemphigoid requiring hospitalization have been reported with DPP-4 inhibitor use. In reported cases, patients visit web page recovered with topical or systemic immunosuppressive treatment and discontinuation of the DPP-4 inhibitor.
If bullous pemphigoid is suspected, JANUVIA should be discontinued and referral to a dermatologist should be considered for diagnosis medication appropriate treatment.
The Januvia kidney disease medication Guide also is available. JANUVIA is indicated as an adjunct januvia kidney disease medication diet and exercise to januvia kidney disease disease medication control in adults with type 2 diabetes mellitus.
Selected Safety Information JANUVIA is contraindicated in patients with a history of a serious januvia kidney disease medication reaction to sitagliptin, such as anaphylaxis or angioedema. Indication Januvia kidney is indicated as disease medication adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.
Indication Selected Safety Information.
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