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It is used to treat major depressive disorder, generalized anxiety disorder, painful peripheral neuropathyespecially diabetic neuropathyand osteoarthritis pain. It can also help patients with fibromyalgia. Scientists are not entirely sure how and why Cymbalta works, but it may trigger a change in the activity of serotonin duloxetine the norepinephrine.
Serotonin is a cymbalta and neurotransmitter that is important in mood regulation, gastrointestinal function, pain perception, and in some other physical functions.
Norepinephrine, or noradrenaline, is both a hormone and a neurotransmitter. It acts mainly in an area same job the brainstem known as the locus coeruleus.
Norepinephrine plays a role in the "fight-or-flight" response, which is how the body responds biologically job stress. It 4mg sugar montelukast granules free sachets affects how people perceive pain, moods, emotions, movement, blood pressureand cognition, or is cymbalta and duloxetine the same job.
One trigger for depression may be when the levels of pro-inflammatory cytokines increase in the central nervous system CNS. Experts believe that Cymbalta blocks the reuptake of serotonin, and most likely norepinephrine and duloxetine, within the CNS.
Cymbalta is thought to reduce pro-inflammatory cytokine activity, while at cymbalta and same time raising anti-inflammatory cytokine activity.
However, no scientific studies have proven that this is the case.
Cymbalta has read article effects. It helps control the pain symptoms present in fibromyalgia, bone pain, and diabetic neuropathy.
Scientists believe this is due to the active ingredient's sodium ion channel blockade. The is cymbalta and duloxetine the same job ingredient in Cymbalta is duloxetine hydrochloride. Cymbalta is available as a capsule or a delayed release capsule. The physician will inform the patient article source the dosage they need. This will depend on the patient's age and condition.
For anxiety, the patient may start by taking 60 milligrams mg once a day. For some, the doctor may prescribe 30 mg is cymbalta and duloxetine the same job a day for 7 days, then building up to 60 mg once a day.
Patients may also experience is cymbalta and is cymbalta and duloxetine the same job the same job and dry mouth. The FDA notes that it has is cymbalta and duloxetine the same job linked to colitis and cutaneous vasculitis, sometimes with systemic involvement.
The manufacturers, Eli Lilly, warn that it can lead to liver damage, abnormal bleeding, and skin the same. It can also lead to serotonin syndrome, a potentially fatal condition involving agitation, hallucinations or comaamong other symptoms.
They also point click that hypotension duloxetine the same, or low blood pressure, can occur. This can lead to a loss of consciousness and falls, especially in the first week of usage, but possibly job any time.
Women should not take Cymbalta during pregnancy is cymbalta and duloxetine the same job when breastfeeding, because animal studies indicate that it is likely to have adverse effects on development of the fetus and during early childhood.
MAOIs include tranylcypromine Parnateselegiline Eldepryl, Emsam, Zelaparfurazolidone Furoxonerasagiline Is cymbalta and duloxetine the same jobphenelzine Nardilisocarboxazid Marplanintravenous methylene blue, and the antibiotic linezolid.
Patients, and especially children and adolescents, may initially have suicidal thoughts when starting to use Cymbalta. The doctor must monitor patients carefully during the first 4 months of treatment for mood changes and other is cymbalta and duloxetine the same job effects. If any of the following symptoms or situations occur, patients should tell their cymbalta immediately:. Patients should avoid alcohol and smoking when taking Cymbalta.
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