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Severe renal impairment eGFR 2.
Metabolic acidosis, diabetic ketoacidosis. Suspend therapy if dehydration occurs or before surgery.
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B 12 in susceptible patients.
Increased risk of lactic acidosis with topiramate, other carbonic anhydrase inhibitors eg, zonisamide, acetazolamide, dichlorphenamide ; monitor. Concomitant cationic what that interfere with renal tubular transport systems eg, ranolazine, vandetanib, dolutegravir, glucophage 500mg for what may increase metformin levels; monitor. Avoid excessive alcohol intake potentiates effects of metformin on lactate. Diuretics, what, phenothiazines, thyroid products, estrogens, oral contraceptives, phenytoin, sympathomimetics, glucophage 500mg for what channel blockers, isoniazid, nicotinic acid, others may cause glucophage 500mg for what. Diarrhea, nausea, vomiting, flatulence, asthenia, indigestion, abdominal discomfort, headache; rare: Generic Name and Formulations: Metformin HCl mg, mg, mg; tabs.
Adjunct to diet and exercise in type 2 diabetes. XR and diabetes weight Tabs mg—, ; mg, mg—
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