Clinical studies have famvir medicine institute been conducted in HSV-infected patients immunocompromised for other causes than HIV-infection see section 5. Treatment should be initiated as soon as possible famvir medicine institute a diagnosis of herpes zoster or ophthalmic zoster. First episode of genital herpes: Article source of treatment is recommended as soon as possible after a diagnosis of first episode of genital herpes.
Episodic treatment of recurrent genital herpes: Initiation of treatment is institute as soon as possible after onset of prodromal symptoms e.
Suppressive therapy should be discontinued after a maximum of 12 months of continuous antiviral therapy to reassess recurrence frequency and severity. The famvir medicine institute period of reassessment should include two recurrences.
Patients who continue to have significant disease may restart suppressive therapy. Because reduced clearance institute penciclovir is related to famvir medicine institute renal function, as measured by creatinine clearance, special attention should be famvir medicine institute to doses in patients with impaired famvir medicine institute function.
Famvir medicine institute recommendations for adult patients with renal impairment are famvir medicine institute in Table 1.
Indication and nominal dose famvir medicine institute. Institute herpes in immunocompetent adults — episodic treatment of recurrent genital herpes. Genital herpes in immunocompromised adults — episodic treatment of recurrent genital herpes. The recommended dose regimens for haemodialysis patients are included in Table 1.
No dose adjustment is required in patients with mild or moderate hepatic impairment. No data are available for patients with severe hepatic impairment see sections 4. Famvir medicine institute safety and institute of famciclovir in children and adolescents click at this article source less than 18 years have not been established. Currently famvir medicine institute data are described in sections 5.
In patients with impaired renal function dose adjustment is necessary see sections 4. Famciclovir has not been studied in patients with severe hepatic impairment.
Conversion of famciclovir to its active metabolite penciclovir may famvir medicine impaired in these patients resulting in lower penciclovir plasma concentrations, and thus a decrease of efficacy of famciclovir may occur. Clinical response should be closely monitored, particularly in immunocompromised patients.
Consideration should be given to intravenous antiviral therapy when /tab-lithium-carbonate-q-sirve.html to oral therapy is institute insufficient. Institute with complicated herpes zoster, i.
Moreover, immunocompromised patients with ophthalmic zoster or those with a high risk for disease dissemination famvir medicine institute visceral organ involvement should be famvir medicine institute with intravenous antiviral therapy.
Patients should be advised to avoid intercourse when symptoms are present famvir medicine institute if treatment with an famvir medicine institute has been initiated. During suppressive treatment with antiviral agents, the frequency of viral shedding is significantly reduced.
However, transmission is still possible. Therefore, in addition to institute with famciclovir, it is recommended that patients use safer institute practices. Institute with rare famvir medicine problems of galactose intolerance, the Famvir medicine lactase deficiency or glucose-galactose malabsorption should not take institute medicinal product.
Concurrent use of probenecid may result in famvir medicine institute plasma concentrations of penciclovir, famvir medicine active metabolite institute famciclovir, by competing for elimination. Therefore, patients receiving famciclovir at a dose of mg three times daily co-administered with probenecid, should be monitored for toxicity.
If patients experience institute dizziness, somnolence, confusion or other central nervous system disturbances, a dose reduction of famciclovir to mg institute times daily famvir medicine institute be considered. Famciclovir needs aldehyde oxidase to be converted into penciclovir, its active metabolite. Raloxifen has been shown to be a potent inhibitor of this enzyme in vitro. Co-administration of raloxifene could affect the formation of penciclovir and thus the efficacy of famvir medicine institute.
When raloxifen institute co-administered with famciclovir the clinical efficacy of the antiviral therapy should be monitored. Patients with genital famvir medicine should be advised to avoid intercourse when symptoms are present even if treatment has been initiated.
It is recommended that patients use safer sex institute see section 4. There is a limited amount of data less than pregnancy outcomes from famvir medicine institute use of famciclovir in pregnant women.
Based on these limited amounts of information, the cumulative analysis of both prospective famvir medicine institute retrospective pregnancy cases did not provide evidence indicating that the product causes any specific foetal defect or congenital anomaly.
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