Cefuroxime is one of the bactericidal second generation cephalosporin antibiotics, cefuroxime axetil with clavulanic acid cefuroxime axetil with clavulanic acid active against a wide range of Gram-positive and Gram-negative susceptible organisms including many beta-lactamase see more strains.
Cefuroxime axetil with clavulanic acid is indicated for the treatment of infections caused by sensitive bacteria. Clavulanic acid has a similar structure to the beta-lactam antibiotics but binds irreversibly to the beta-lactamase enzymes. Clavulanic acid protects Cefuroxime from degradation by beta-lactamase enzymes and effectively extends the antibacterial spectrum of Cefuroxime to include many bacteria normally resistant to Cefuroxime and other cephalosporins.
The peak serum Cefuroxime concentration after a 1. Drugs that reduce gastric acidity may result in a lower cefuroxime axetil with of Cefuroxime clavulanic acid Clavulanic acids compared with that of fasting cefuroxime axetil with clavulanic acid and tend to cancel the effect of postprandial absorption. It is contraindicated in patients with known allergy to Cefuroxime cefuroxime axetil with clavulanic acid Clavulanic acid or to the cephalosporin group of antibiotics.
Generally Cefuroxime cefuroxime axetil with clavulanic acid Clavulanic acid are well tolerated.
However, a few side effects like nausea, vomiting, diarrhea, abdominal discomfort or pain may occur. Both Cefuroxime and Clavulanic acid are pregnancy category Click here. Check this out is excreted in cefuroxime axetil with clavulanic acid milk; cefuroxime axetil with clavulanic acid should be given to discontinuing nursing temporarily during treatment with Cefuroxime.
Cefuroxime should be given with caution to patients receiving concurrent treatment with potent diuretics because these diuretics are suspected of adversely affecting renal function. Cefuroxime, as with other broad-spectrum antibiotics, should be prescribed with caution in individuals with a history of colitis.
Overdosage of Cefaclav can cause cerebral irritation leading to convulsions.
Serum levels of Cefaclav can be reduced by haemodialysis and peritoneal dialysis. Available Brand Names View Details. Novelta Bestway Pharmaceuticals Ltd.
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