Sexual pharmacotoxicity renders patients with epilepsy at a risk can topamax cause seizures erectile dysfunction sexual dysfunction SD.
This study is aimed to analyze the relationship between sexual function and topiramate to avoid topiramate-associated SD.
A total of 17 publications were reviewed. Based on limited polytherapy observational studies, the frequency of self-reported topiramate-associated SD, libido disorder, and can topamax cause seizures erectile dysfunction disorder in patients with polytherapy was 9. Female patients mainly had anorgasmia, whereas male patients principally had erectile dysfunction. The daily dose of topiramate in patients with SD was within the recommended dose.
Sexual adversity usually occurred from 4weeks after topiramate use but can topamax cause seizures erectile dysfunction subsided without eventful complications after topiramate substitution or dose reduction in all patients. Topiramate can elicit different patterns of SD, especially anorgasmia in women and erectile dysfunction in can topamax cause seizures erectile dysfunction, even with a therapeutic dose.
Can topamax cause drug education and careful monitoring are necessary to maximize sexual health, especially in persons undergoing polytherapy and with other risks for SD. Moreover, a seizures erectile dysfunction response, such as substitution can topamax cause seizures erectile dysfunction reduction of the dose, is suggested when SD occurs during its use.
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