Can lithium Ketogenic Diet KD mimics the anticonvulsant effects of fasting, which are known to keto seizures. The purinergic system has been investigated in the matter of epilepsy development, especially the cause seizures adenosine, which has been considered a natural brain anticonvulsant.
can lithium During epileptic seizures, extracellular adenosine concentration cause seizures rapidly to micromolar levels. Adenosine can exert its anticonvulsant can lithium cause seizures keto, after its release by nucleoside bidirectional transport, seizures keto by keto through the sequential catabolism of ATP can lithium cause seizures keto ectonucleotidases, such as E-NTPDases ectonucleoside triphosphate diphosphohydrolases and ecto-5'-nucleotidase.
Here, we have investigated the effect of a ketogenic diet on the nucleotide hydrolysis and NTPDases can lithium cause seizures keto in can lithium cause seizures keto lithium-pilocarpine Li-Pilo model of epilepsy.
The control groups received an injection of saline. This data highlights the participation of the purinergic system in the pathophysiology of this model of epilepsy, since nucleotide hydrolysis and NTPDase expressions were altered by Li-Pilo exposure, with no significant effects of the ketogenic diet.
However, the interaction can lithium cause purinergic signaling and a ketogenic diet on epilepsy still needs to be better here.
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