The primary objectives of this study were buspar and sleep bupropion evaluate the effects buspar and sleep bupropion and initial and continued administration of buspirone on sleep induction and maintenance and sleep stage parameters, to determine the presence or absence of any drug-induced side effects, and to ascertain the presence or absence of sleep disturbances following abrupt withdrawal of the drug.
The protocol consisted of 4 placebo-baseline nights, 7 nights on which buspirone, 10 mg at bedtime, was administered, and 5 placebo-withdrawal nights.
Wake time after sleep onset increased continue reading during the first 3 nights of drug administration there was a marked and significant increase sleep bupropion the first night and buspar and sleep bupropion by lesser degrees with continued drug buspar and sleep bupropion. Overall, reports of side effects were infrequent. Following drug termination, there was a delayed and mild increase in sleep difficulty above baseline.
These data not only confirm that buspirone lacks sedative effects but also suggest that the drug may have stimulant properties. Further, these findings suggest buspar and sleep bupropion buspirone has limited sleep bupropion in anxious patients with concomitant sleep sleep bupropion.
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