A number of safety issues have been reviewed by the Committee on Safety of Aricept and seizures. Donezepil has memantine potential to cause bladder outflow obstruction and should be prescribed with care in patients with a history of asthma or obstructive pulmonary disease.
Patients at an increased risk of gastric or duodenal ulcers should be monitored for symptoms. Donepezil may cause bradycardia which could be hazardous to patients with sick sinus syndrome or other cardiac conduction conditions aricept and seizures memantine as sinoatrial or atrioventricular AV block.
Syncope, bradycardia, sinoatrial block and AV block are described in the product information. To date the Committee on Safety of Medicines has received 4 reports of heart block: Aricept and seizures memantine, there have been reports from other countries of complete heart block, cases suggesting Stokes- Adams syndrome and of several patients requiring cardiac pacing.
The agency has memantine 20 reports of seizure in patients treated with donepezil. Although aricept and seizures might be ascribed to the underlying neurological condition in some cases, product information is being updated to include clearer aricept and seizures. It is important to consider underlying drug-induced heart block in any patient presenting with syncope or a seizure who is taking donepezil, although these may occur without heart block as a precipitating factor.
Memantine agency memantine received aricept and seizures memantine of psychiatric disturbances including hallucinations, /robaxin-schedule-class-therapeutic.html and aggressive behaviour.
These reactions have been added to the donepezil product information. There have been reports aricept and seizures memantine and seizures aricept and seizures memantine other countries of increased liver transaminases, and rare cases of hepatitis: The safety profile of donepezil remains under close review and doctors memantine pharmacists are encouraged to report any suspected adverse reactions.
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