The efficacy of the drugs currently available for treatment of infection with Trichuris trichiura is low compared with that of the drugs used against roundworm and hookworm.
Single-dose combinations of albendazole with ivermectin or of albendazole with diethylcarbamazine DEC have recently been seen to produce raid and sustained reductions in Wuchereria bancrofti microfilaraemia. This observation prompted the present study, on the efficacy of these combinations albendazole and ivermectin brand name trichuriasis.
Most of the children years of age who each provided a single, pre-treatment, stool sample were found positive for Trichuris ova. Albendazole and ivermectin brand name were each randomly allocated to one of the three treatment groups and checked for infection 3 weeks post-treatment, again by a single stool albendazole and ivermectin brand name.
Single-dose therapy with albendazole plus ivermectin produced a albendazole and ivermectin brand name rate' The efficacies of albendazole with DEC and of albendazole alone were statistically albendazole and ivermectin brand name. Single-dose treatment with the albendazole-ivermectin combination appears to be highly effective against trichuriasis and could prove valuable for routine use.
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